Tizanidine and alcohol reddit. It has many possible drug interactions.

Tizanidine and alcohol reddit However, agree with other posters that long term effects will hurt your game. So she does have some zanaflex 4mg and figured 2 of those and maybe two string screwdrivers would give the desired effect. Some tramadol interactions raise the risk of side effects from tramadol. While effective for short-term relief, questions often arise such as: Is tizanidine addictive? Is Zanaflex habit forming or even a controlled substance? These concerns are valid, especially for individuals using tizanidine long-term or outside prescribed parameters. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. The noradrenergic system is an important neurotransmission system implicated in the occurrence of alcohol withdrawal symptoms and anxiety leading to relapse during abstinence from alcohol usage. com Tizanidine is a short-acting muscle relaxant and is used to treat spasticity. Aug 15, 2025 · Learn about the side effects of tizanidine, from common to rare, for consumers and healthcare professionals. Is it okay? I got prescribed . It comes with a bit of caution; i've mixed it with alcohol, but that's probably not advisable as tizanidine is hard on the liver. tizanidine for anxiety. 16 votes, 53 comments. They are contraindicated together. Google turned up a vaguely similar thread, although it’s 6 years old so I figured I’d start a new one. I'm especially interested in the effects it has on the CNS. Tizanidine is a muscle relaxer. Have you tried talking to your doctor about needing more relief? Do you see a pain management specialist? I’d keep trying til someone can and does help Reply reply Tasty-Instruction-78 • Apr 16, 2025 · Tizanidine, commonly sold under the brand name Zanaflex, is a prescription muscle relaxer used to treat muscle spasms and cramping. I take tizanidine, but for it's muscle relaxant properties because I have some nerve damage in my lower back. These combos can have severe effects. I've never noticed as to whether or not it helps my ADHD symptoms. 7K subscribers in the CRPS community. Alcohol can intensify the drowsiness and Alcohol should be avoided if you are under treatment with a centrally-acting muscle relaxant (like cyclobenzaprine, baclofen, methocarbamol or tizanidine). My friends all have gotten so many messages from me that I don't even remember sending because of tizanidine. Sep 11, 2024 · Alcohol increases the peak concentration of tizanidine and also the likelihood of side effects. Here’s what you should not take with tizanidine to avoid side effects. 5 mg nightly. I’ve been seeing conflicting information online and I was wondering if anyone had any thoughts on this. . I saw secret walls of red text crawling across my phone screen. Klonopin is the brand name for an anti-anxiety medication, with the generic name of clonazepam. i have seen some talk about this medication in the subreddit before but not for a long time. Tizanidine tablet is a central alpha-2-adrenergic agonist indicated for the management of spasticity. Explore the comprehensive guide to understanding this medication. A subreddit for Zanaflex. I could watch hair grow. I do get a pretty relaxing high when I snort tizanidine, but I would recommend it, but just be careful with the dosage, I usually snort a 1. May 26, 2024 · Drugs That Can Cause Erectile Dysfunction If you’re having problems getting an erection, you might want to look in your medicine cabinet first. Aug 11, 2024 · Find patient medical information for Tizanidine (Zanaflex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings There’s a ceiling with Tizanidine ime. 5 mg (3/4 of a pill) in a day, helps me sleep, but I don't do it everyday, also ingesting it (like 8mg or more) does a pretty good job for me The sciatica subreddit is the internet's largest community to find support, share stories (successful or otherwise!), and learn more about the challenging medical condition of radiculopathy. Tizanidine recreational value? Was given about 30 ct. Oct 30, 2025 · Use WebMD’s Drug Interaction Checker to identify potential interactions between medications, supplements, and foods. tizanidine is indeed a muscle relaxant, but unlike "fun" gabaminergic muscle relaxants like carisoprodol, tizanidine is an a2 adrenergic agonist, like blood pressure med clonidine, so I doubt it would be fun to get high off of, or even possible, but I can guarantee you that people have tried. com. FDA warns about serious risks and death when combining opioid pain or cough medicines with benzodiazepines; requires its strongest warning Adderall ir, lamictal, seroquel, tizanidine, and now adding viibryd. Tizanidine has been a nightmare for me. com Nov 11, 2025 · Mixing Tizanidine and Alcohol be harmful to the body because both can slow down the functioning of your nervous system, which may result in undesirable side effects. Learn why you shouldn't mix them and what to do if you already have. Reduce side effects and support safer treatment decisions. Zanaflex is a medication that is used to treat muscle spasticity due to spinal cord injury or multiple sclerosis. Effectiveness appears similar to baclofen or diazepam Apr 10, 2024 · Can you take tizanidine after drinking alcohol? Tizanidine is a muscle relaxant commonly prescribed to treat muscle spasms and increased muscle tone associated with conditions like multiple sclerosis or spinal cord injuries. Jul 28, 2025 · Mixing alcohol and diazepam comes with serious dangers and risks. Female 33 years old Medications; topiramate, tizanidine, Percocet, Lyrica Medical history; CRPS, inappropriate sinus tachycardia, PCOS No drugs, minimal alcohol use, and I vape occasionally. No tolerance, 4mg insufflated seems to be where most end up getting sedated. But Tizanidine blocks pain sensations and is an Alpha-adrenoceptor agonist (α-agonists), meaning that it binds to α-receptors on vascular smooth muscle and induces smooth contraction and vasoconstriction, thus mimicking the effects of sympathetic adrenergic nerve activation to the blood vessels. Because of the short duration of therapeutic effect, treatment with tizanidine tablets should be reserved for those daily activities and times when relief of spasticity is most important [see Dosage and Administration (2. Here are the risks. Here are several common and serious side effects to watch out for as you’re taking this medication. It’s a bummer because I slept the best I had in years. Some increase side effects like drowsiness. 1)]. So my play partner really wants to really have a CNC session soon. Thoughts?? We would like to show you a description here but the site won’t allow us. This is what tizanidine does to me. Nov 23, 2021 · Tizanidine is a prescription drug that can cause addiction to develop. Just wondering would this be effective and Aug 9, 2024 · Avoiding tizanidine and alcohol: Muscle relaxers and alcohol are best avoided, here’s why. My doctor said it was okay to take this with alcohol (though she said it’s not advised due to enhanced side effects). Alcohol While there’s not a direct interaction between the two, you may want to use caution with alcohol while taking methylprednisolone. Tizanidine blood levels and effects are increased by some of my other meds (including Famotidine), so I cut the 2 mg tablets in quarters and take only around 0. Is the interaction between tizanidine and opioids comparable to that of benzos and opioids? 342 votes, 128 comments. (for muscle spasms) Has anyone tried this drug? Was it effective? hey guys! i was wondering what your experiences are with tizanidine (zanaflex). Liver enzymes (specifically aminotransferase) should be monitored when starting treatment, when clinically indicated, and for at least one month after the maximum dosage is achieved. Alcohol and methylprednisolone can both suppress the immune system. Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. It is a type of muscle relaxant used for very specific types of muscle spasms. This makes it easier to get (or recover from) an infection, especially if you drink in large quantities. Jul 24, 2025 · And while alcohol is paired with aggression, with half of all violent crimes and sexual assaults being influenced by alcohol, it doesn’t seem like ADHD medication increases that. Tizanidine safe to consume recreationally? Title says it all, would be thankful if you could also tell me how to dose or what your experienxe was. [3] Nov 3, 1999 · Makes sense, with tizanidine's biological half life of roughly 2-3 hours, so most of the medication should essentially be out of my system within 4-6 hours. I Tizanidine was the only thing that worked for me before my surgery. The primary use of tizanidine is to relieve increased muscle pain and muscle tone associated with multiple sclerosis. Learn more about mixing alcohol and diazepam, and how to find treatment. Tizanidine is a medication where you increase the dosage very slowly while being monitored by a doctor in order to minimize the potential for side effects. 4 days ago · Learn about Tizanidine side effects, uses and potential risks of addiction associated with tizanidine. Apr 17, 2023 · Tizanidine is a muscle relaxant that may help minimize muscle spasms. New pain management doctor just switched me from Soma to Tizanidine. I can't take it anymore because my blood pressure medication (prescribed for migraines) was increased. 68 votes, 21 comments. Jun 24, 2019 · Muscle relaxers and alcohol can have potentially dangerous interactions. 49% of reviewers reported a positive experience, while 29% reported a negative experience. Tizanidine User Reviews & Ratings Brand names: Zanaflex, Ontralfy Tizanidine has an average rating of 6. See full list on drugs. Sertraline (Zoloft), trazodone, and tizanidine are other common culprits. Source: Rheumatoid Arthritis, take tizanidine and diazepam, chronic facial pain (I have trigeminal neuralgia! Tizanidine literally made me visually hallucinate. When i get fairly drunk though, my inhibitions lowered and such, i tend to take like half a pill or so. I wanted to know if anyone has some information on the interactions of tizanidine and alcohol, benzodiazepines, and opioids respectively. I started at 2 mg and didn’t fall asleep for hours (took it 8 pm and fell asleep at 11), then went up to 4 mg and the insomnia is worse (falling asleep around 1:00 am). Tizanidine and alcohol? Honestly not really sure if this is the right sub for this question, but I’m prescribed a dose of tizanidine every night before bed for my neck muscles. 5. Oct 20, 2022 · 9. A community of headache disease sufferers. Every other I was given had no effect. May 4, 2021 · What is Tizanidine? Tizanidine is an oral drug that is available both in generic and brand name. However it’s more sedating for me but not for everyone. Combining Lunesta with alcohol consumption is warned against as the side effects of Lunesta are very strong and, when coupled with alcohol, they can be devastating. Sep 13, 2024 · Explore tizanidine's addiction potential, signs, risks, and treatment options for a safer approach to muscle relaxation. The fifth pair was griseofulvin, an antifungal medication, and a hormone-based oral contraceptive sold under various brand and generic names. Because of the short duration of therapeutic effect, treatment with tizanidine hydrochloride capsules should be reserved for those daily activities and times when relief of spasticity is most important [see DOSAGE AND ADMINISTRATION (2. These include weakness, fatigue (low energy), and increased frequency of urination. Examples include sleepiness, an increased risk of seizures Tizanidine oral tablet is prescribed for muscle stiffness and spasms in adults. Here are 11 of the most common interactions to look out for. Expert insights on overcoming abuse of this muscle relaxant. Nothing in this forum should be… Nov 1, 2025 · Tizanidine is used to help relax certain muscles in your body. Does this apply to all medications metabolized by 1A2? I’m just wondering why it’s so tizanidine specific. Tizanidine hydrochloride is indicated for the management of spasticity. This was associated with an increase in side effects of tizanidine. Today is my last day on them and aside from my stomach being a mess, everything Aug 23, 2024 · Alcohol is an intoxicating, ethanol-based substance typically found in hard liquor, malt liquor, beer, or wine. Tizanidine is Clonidine and Alcohol Mix. Even at that low dose, it causes mood instability, irritability, anxiety, panic, restlessness, and hypomania symptoms. 123K subscribers in the migraine community. New comments cannot be posted and votes cannot be cast. It's used to treat muscle spasms caused by certain conditions such as multiple sclerosis, ALS, or spinal cord injury. Alcohol and meth bad combo for heart health mate and throwing tizanidine on top off that isn't bright. Feb 20, 2020 · Tizanidine Uses, Dosage, Side Effects - Drugs. They’re great for mixing with opiates when your opiate tolerance gets sky high too, not the safest thing but safer then mixing benzo’s and probably alcohol too. It’s a muscle relaxant drug that may cause mild or serious side effects. Initially we were going to get ketamine but my connect wasn't able to get any. When muscle relaxants are combined with alcohol (ethanol), side effects may occur such as: Feb 19, 2020 · Discover professional recommendations for managing Tizanidine and alcohol interactions and essential insights on avoiding other medication complications. It was hard for me to find useful information on the matter. I think the effect of 4mg intranasally (and with food) was more intense than the same dose orally, in a fasted state. (I also drink alcohol) Is taking this many medications/this combo dangerous? I see a Psychiatrist. As someone who has experimented with a lot in places most wouldn’t, I’m curious as to what to expect mixing these together. Examples include gabapentin (Neurontin), cyclobenzaprine (Flexeril), and alcohol. Sep 29, 2021 · Learn about Modafinil and alcohol: the result of mixing both substances and how the drug interacts with other medications. Oct 31, 2023 · Tizanidine (Zanaflex) interacts with alpha-2 agonist drugs, birth control medications, opioids, sedatives, and other medications. It is usually prescribed for medicinal purposes but it is taken as overdose and frequently abused. Overall, tizanidine is not the first go to muscle relaxer because it tends to have worse side effects and more interactions. What is Tizanidine? Tizanidine is a short-acting muscle relaxant, prescribed mainly for reducing pain associated with multiple sclerosis, ALS or spinal cord injury. Mine is tizanidine and ciprofloxacin, because it is so off the wall random to me. I snorted two 4mg pills yesterday (8mg total) and not only did I love it but I also blacked out for maybe 4-5 hours. Sep 11, 2024 · Tizanidine and Alcohol Interactions. blood pressure drug verapamil and colchicine, used to treat gout. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, including multiple sclerosis or certain injuries to the spine. 1mg twice daily of clonidine to control my blood pressure. Nov 28, 2023 · Propranolol can interact with many medications and substances. We would like to show you a description here but the site won’t allow us. I only take it at night because it's a strong sedatives. Alcohol is the other one. When snorted it comes on extremely fast and feels very extremely similar to that of Xanax or other Tizanidine and weed can cause an overdose, Marijuana alone isn't deadly but when mixed with certain prescription medications can be fatal and Tizanidine is one of those. Tizanidine can play a role in alcohol withdrawal since it interferes with the noradrenergic system neurot … Apr 1, 2024 · It’s best to avoid combining alcohol and muscle relaxers. I’ve used it but tizanidine works better. Tizanidine and diazepam together can cause some central nervous system depression (like a reduced respiratory drive), but unless you take a ton of both of them, you’re probably okay. Wait, did you take the tizanidine with the beer? I was told you can never take it with alcohol. Like the first thing they say about that medication is that it has serious interactions with alcohol like bradycardia. Learn why you should never mix these substances. They may mix alcohol with Ambien and Xanax in their attempts. Sep 25, 2025 · Is Tizanidine Addictive?—Tizanidine is a prescription muscle relaxant but misuse, high doses or long use causes dependence and side effects. The brand name version is called Zanaflex. Official subreddit for Complex Regional Pain Syndrome. Learn about tizanidine addiction risks, withdrawal symptoms, and effective treatment options. I was taken 4mg as well, three times a day. I was recently in the hospital for sepsis caused my pneumonia and was sent home on Amoxicillan (BID) and Azithromycin (QD). I took the Tizanidine about 15 minutes ago. Just be careful can make you a little drowsy. Tizanidine is a short-acting muscle relaxer that's marketed under the brand name Zanaflex. Oddly though, I cannot sleep on it. It’s an actual listed, but rare, side effect. I have 2mg pills. Another pair — the antibiotic ciprofloxacin and the muscle relaxant tizanidine — could cause patients to pass out. Tizanidine is also a medication that interacts with a LOT of other meds. thanks! Reply reply oomio10 • we would see a unique AUC change for other 1A2 substrates Reply reply More repliesMore replies omairville • Increased dizziness, risk of hypotension and overall fx of tizanidine Reply reply exiled123x • I only realized it was a drug interaction between tizanidine and seroquel when I decided to stop Seroquel to see if that was the issue and out of the blue when I was picking up a different prescription the pharmacist mentioned that taking seroquel and tizanidine together can cause this exact side effect. May 23, 2022 · If mixed, alcohol and muscle relaxers can produce a variety of dangerous effects for women. It can actually be savored through the mucous membranes meaning it absolutely indeed is water soluble. Dec 2, 2024 · As with all medications, tizanidine may have side effects. 2 out of 10 from a total of 391 reviews on Drugs. of 4mg tizanidine and was told i could snort them. Learn about the signs of tizanidine use and the dangerous effects of abusing the drug. It has many possible drug interactions. Mind you during this upcoming play session Molly and weed are gonna be taken too. Alcohol increased the AUC of tizanidine by approximately 20%, while also increasing its C max by approximately 15%. Baclofen acts on gaba receptors primarily (similar to benzos, alcohol, and phenibut as well) whereas tizanidine acts on noradrenergic alpha 2 receptors and because of this tizanidine isn't as dangerous to combine with say Xanax, alcohol, or opiates as baclofen would be because it's not a depressant, it's more like a nerve numbing agent Jan 1, 2025 · Tizanidine is a short-acting muscle relaxant and is used to treat spasticity. What does Tizanidine do? Tizanidine works on the central nervous system to Aug 3, 2023 · Learn about tizanidine (Zanaflex) usage and dosing. Meaning a side effect already for it already is brachycarida, then alcohol makes that worse. These are muscle spasms experienced by individuals with spinal cord injuries and Multiple Sclerosis. If I had a few alcoholic drinks 12-15 hours ago, can I take muscle relaxer (tizanidine) OR codeine now? Some drugs or even a little alcohol may help short term , maybe over a few hours of play or feel like it’s needed to play at a higher level. i started tizanidine in december 2020 for muscle spasms in my back, neck, and shoulders - its somehow the first time that… Jun 10, 2024 · Tramadol (ConZip, Qdolo) is an opioid medication used to treat pain. Whether migraines, cluster headaches… Nov 11, 2021 · Learn how tizanidine withdrawal and detox can be challenging to certain individuals with particular health risks, and understand how to best eliminate addiction to the muscle relaxant. However, I almost always take dramamine, hydroxyzine, promethazine, or diphenhydramine with oxys or other opis, so the sedation from the antihistamines combined with the euphoria of the oxy seems to match well with Tizan lines. truegot prescribed tizanidine, anyone have experience with using it here? Tizanidine Interactions There are 656 drugs known to interact with tizanidine, along with 4 disease interactions, and 3 alcohol/food interactions. Anyway, in respect to substances being taken before a tattoo, what substances can reduce pain and what can increase pain? How might these affect the healing process or ink retention? I’m wondering about OTC painkillers like Acetaminophen (Tylenol), Naproxen (Aleve), Opioids (Codeine My pain doc started me on Tizanidine this week and it’s done wonders for my anxiety, burning pain, pins and needles and POTS symptoms. Aug 2, 2010 · i think there is definitely recreational value to tizanidine--most present when mixed with other things. Tizanidine is a powerful muscle relaxant prescribed to treat muscle spasms and other related conditions. If I want to drink (I have no interest in mixing the alc+muscle relaxer) , how long should I wait after a dose to? Dec 4, 2024 · Mixing tizanidine and alcohol is strongly discouraged, as combining these substances may lead to dangerous side effects. Learn more about tizanidine, including its uses, dosage, and potential side effects and warnings. Comparing muscle relaxers: Read on for the differences and similarities between several muscle relaxers available to treat muscle stiffness. Of the total drug interactions, 251 are major, 403 are moderate, and 2 are minor. Tizanidine, medicinal wax, and alcohol. Side effects of muscle relaxants can be intensified by drinking alcohol. I have a close family member with MS who takes this daily, has for quite some time & will continue to do so indefinitely if possible. However, a common concern among individuals taking tizanidine is whether it is safe to consume alcohol while on this medication. Will this make me OD or will it just make me pass the fuck out. trueWe do NOT promote drug use; - Accept, for better and or worse, that licit & illicit drug use is part of our world and choose to work to minimize its harmful effects rather than simply ignore or condemn them; - Utilize evidence-based, feasible, and cost-effective practices to prevent and reduce harm; - Call for the non-judgmental, non-coercive provision of services and resources to people Will alcohol potentiate the living hell out of this muscle relaxer? I took about 7 shots of Captain Morgan (35% alc per volume) and a 4mg Tizanidine. Jun 30, 2020 · Addicts combine drugs when in search of a new high. Levofloxacin does not have this interaction, and is safe with tizanidine. Whats the effects like when its taken this way? How much should i dose? Any combinations to avoid? Archived post. I have a script for 30 4mg Tizanidine pills. Can you guess why? Cipro inhibits CYP1A2, which metabolizes tizanidine, causing a 10-fold increase in tizanidine Cmax, leading to respiratory depression, bradycardia, hypotension, possibly death. Learn about side effects, interactions and indications. Here’s what you should know. hjriu qqfv ayhv neqcb mxzxr vilkm lsglod crzr setp szrzj jzqz nmmn kgsi tcns mpefn